From DNA to Life: Decode the noncoding genome

About:

Gene regulation is fundamental to the developmental intricacies of higher eukaryotes. RNA acts as a hidden regulatory layer, guiding the interpretation of the genome during transcription and contributing to the formation of the myriad cell types in our bodies. I will discuss our research on uncovering novel patterns within the non-coding genome that shape nuclear structure and function, aiming to grasp the universal principles governing cell fate.

Bio:

Xiaohua Shen earned her Ph.D. from the University of Michigan and completed postdoctoral training with Stuart Orkin at Harvard Medical School. She is currently a Cheung Kong Scholar and Professor at Tsinghua University's School of Medicine. Her research focuses on deciphering the impact of non-coding genome regions on chromatin structure, gene expression, and stem-cell fate in development. Additionally, Xiaohua serves as a reviewing editor for eLIFE and sits on the Editorial Boards of Cell Reports, EMBO Reports, and Molecular Omics.

Host PI: Diana Guallar. Epitranscriptomics & Ageing Group, CiMUS

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