Elena Vázquez Sarandeses & Alejandro Sánchez Rueda

Cryo-Electron Tomography reveals the oligomeric assembly of EHD2 and its role at caveolae

Caveolae are plasma membrane invaginations involved in endocytosis. EHD2 is proposed to control their internalization, since its absence leads to an increased mobility of these vesicles. Using Cryo-Electron Tomography, we solved the membrane-bound oligomeric structure of EHD2 and defined the molecular events that explain how EHD2 stabilizes membrane curvature at the neck of caveolae, confining them to the plasma membrane.

CV highlights:

2019 – 2024: PhD in Biochemistry and Structural Biology. Freie Universität Berlin.
2017 – 2019: MSc in Bioengineering. IQS – Ramon Llull, Barcelona.
2012 – 2016: BSc in Biochemsitry. Universitat Autònoma de Barcelona.
 

Elena Vázquez Sarandeses. Postdoc researcher, Gene Regulatory Control in Disease Group

Schwann cell mitochondrial dynamics: the evolution of a thesis

In October 2020 I started my thesis in CiMUS in the field of Schwann cells. We were in the middle of the pandemic, I knew nothing about the city and very little about Schwann cells. This is not only the presentation of my results, but also the process of how I struggled to get them.

CV highlights:

2014-2018: Bsc. in Biochemistry and Biomedical Science in Universitat de València
2018-2019: Msc. in Research in Translational Medicine in Universidad Complutense de Madrid
Currently: PhD student in Gene Regulatory Control in Disease, CiMUS, P1L8

Alejandro Sánchez Rueda. PhD student, Gene Regulatory Control in Disease Group