Happy Thursdays with Neila & Martín
Neila Cosme Boullosa & Martín Kotrulev
PhD students at CiMUS
Theatre room, CiMUS
Development of new neuron-like cellular models for drug discovery in schizophrenia
Drug development is costly and time-consuming, often requiring the use of animal models; however, in vitro cellular models offer a simpler and more ethical alternative. The development of a cellular model mimicking cognitive deficits associated with schizophrenia by differentiating human tumour cells into neuron-like cells would be a useful tool for high-throughput screening campaigns, accelerating preclinical drug discovery.
CV highlights:
2014-2018: Bachelor's degree in Genetics (Universitat Autònoma de Barcelona).
2019-2020: Master's degree in Neuroscience (Universidade de Santiago de Compostela).
2020-present: PhD student in Molecular Medicine at the BioFarma Research Group in CiMUS. Xunta de Galicia fellowship.
Neila Cosme Boullosa. PhD student, Pharmacology Applied to Drug Discovery Group (PSSL2), CiMUS
An unbiased high-throughput screening identifies repurposing drugs and novel molecules that reduce proinflammatory cytokine secretion in the context of Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune chronic disease characterized by progressive inflammatory synovitis. Available therapies target late stages of the inflammation process, when the microenvironment is highly inflammatory and therefore more challenging to control. Developing therapies targeting inflammation upstream would benefit RA patients. We identified and characterized novel and repurposing drugs capable of reducing the secretion of proinflammatory cytokines.
CV highlights:
2015-2019: Bachelor’s degree in Biomedical Engineering (University Rey Juan Carlos of Madrid)
2020-2021: Master's Degree in Biomaterials (University Complutense of Madrid).
2022-present: PhD student in Molecular Medicine. CiMUS, USC/Santander and Xunta de Galicia predoctoral fellowships.
2024: 3-month Stay at Scripps Research, La Jolla, CA, USA (Xunta and SEI grants)
2022-2025: Travel awards and/or oral presentations in national and international congresses (EULAR, ECI, SEI, IUIS)
Martín Kotrulev. PhD student at the Immunity and Small Molecules Group (P0L6), CiMUS.
Attendance certificates will be provided upon request to cimus.xestion [at] usc.es (cimus[dot]xestion[at]usc[dot]es). Please remember to register (name and surname) on the printed sheet.