Happy Thursdays with Raquel & Sara

Biomaterial-based systems for tunable and targeted gene delivery

This work focuses on developing advanced biomaterial platforms for immunotherapy and targeted gene delivery. We designed pDNA-activated hydrogels for the sustained production of pseudotyped immunostimulatory viral nanoparticles. Additionally, we engineered biomimetic nanoparticles functionalized with the rabies virus glycoprotein to improve gene delivery.

CV highlights: 

Raquel Martinez-Campelo is a PhD student at the University of Santiago de Compostela, where she previously earned her degree in Pharmacy and an MSc in Nanoscience and Nanotechnology. Her current work focuses on the design of advanced platforms for the sustained release of immunostimulatory nanoparticles, as well as the development of biomimetic nanosystems to enhance gene delivery efficiency.

Raquel Martínez Campelo. PhD student, Biomaterials & Drug Delivery Group, (P2L6), CiMUS

Alterations in the proteomic profile after bariatric surgery-associated weight loss and their relevance in platelet reactivity and obesity progression

Obesity is associated with a platelet hyperactivation state that promotes the progression of atherosclerosis and fosters a pro-inflammatory and pro-thrombotic environment. My research, involving proteomic and biochemical assays, studied how a significant weight loss following bariatric surgery may reverse this state in obese patients and help reduce the cardiometabolic risk associated with this pathology. 

CV highlights:

Sara Troitiño is a PhD student in Molecular Medicine at CiMUS. She holds a degree in Biotechnology from the University of León and a Master’s degree in Biomedical Research from the University of Santiago de Compostela. She is currently completing her PhD within the Platelet Proteomics group, where her research focuses on how obesity affects platelet reactivity and the progression of atherosclerosis, as well as on the development of novel antiplatelet drugs.

Sara Troitiño Cora. PhD student, Platelet Proteomics Group (PSSL7), CiMUS

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