How does nutrition impact cancer development?

About
Personalized medicine has faced limited success, in part because it often overlooks individual factors, including diet and nutrition. In this talk, I will explore how nutritional status influences cancer development, focusing on the mechanisms linking obesity and how obese state could impact tumor initiation and progression. I will also highlight how specific dietary components may help prevent or reduce cancer aggressiveness, paving the way for more effective, nutrition-informed precision medicine.

Bio
Dr Djouder uses GEMMs and advanced molecular and biochemical technologies to study mechanisms of diseases, with a focus on obesity-related diseases, and with a large expertise on liver conditions.  He discovered how nutrient-driven inflammation contributes to cancer and metabolic diseases, linking NAD⁺ depletion to DNA damage and he pioneered nicotinamide riboside for cancer treatment. His research connected IL-17A to obesity, autoimmunity, and cancer, drawing interest from pharma companies (Lilly, Novartis). He focussed his studies on the URI prefoldin-like complex, revealing its role in nutrient sensing and tumorigenesis. His work, published in high-impact journals earned multiple awards. He was promoted to Senior Group Leader in 2018 despite CNIO’s no-tenure policy. In addition, he has trained over 35 scientists, 80% of whom were women, and 9 PhD students graduated cum laude and continued working in top-labs. None of his students have left science; all have pursued postdoctoral training, reflecting the strength of his educational foundation. His contributions in the research area of nutrients, inflammation, and cancer have been internationally recognized.

Hosted by Rubén Nogueiras. Molecular Metabolism Group, CiMUS

Certificates of attendance will be provided upon request at cimus.xestion [at] usc.es (cimus[dot]xestion[at]usc[dot]es). Please do not forget to enter your name and surname in the printout given during the lecture.