The intricate architecture of the brain is shaped by both external and internal stimuli during critical developmental periods. Understanding the ability of the brain to undergo functional and structural remodeling beyond these periods, will expose the innate mechanisms of adult brain resilience, and their potential implication in the etiology of psychiatric and neurodegenerative disorders. In this seminar, I will provide an overview on my scientific trajectory, sharing my contributions to the development of methods to quantify vascular and axonal plasticity across the entire adult brain. I will also present my latest results, shedding light on the plastic potential of adult brain networks to remodel in response to permanent alterations to the sensory experience.
Alba is a Ramón y Cajal Researcher, and PI of the Brain Plasticity Laboratory at the CIMUS (2023). Previously, she did her PhD in Neurosciences (University of Santiago de Compostela, 2017), and a Postdoc at Nicolas Renier Lab (Paris Brain Institute, 2018-2023). She specialized in the use of tissue clearing and 3D microscopy for the analysis of functional and structural dynamism in the brain. Co-developer of TubeMap, a pipeline for whole-brain reconstruction of the microvasculature (Cell 2020), and developer of new methods to map brain connectivity. Interested in circuit refinement and remodeling from a holistic and multisystem perspective. Research lines: Mechanisms underlying activity-dependent plasticity in the adult brain. Role of internal state-related signals in the refinement and plasticity of brain circuits
This is an internal seminar, that will be chaired by Scientific Director Mabel Loza.
Attendance certificates will be provided upon request to cimus.xestion [at] usc.es (cimus[dot]xestion[at]usc[dot]es). Please bear in mind to register by writing clearly the name and surname on the printed sheet. We will not be responsible for amending the records of anyone who fails to do so.