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CiMUS Seminar

Oxygen sensors-dependent cell metabolic rewiring in disease

Julián Aragonés López

Associate Professor at Universidad Autónoma de Madrid (UAM) and Group Leader of Cellular and molecular responses to hypoxia group in Instituto de Investigación Sanitaria del Hospital Universitario de la Princesa.

29 September 2023 10:00–11:00

Theatre Room, CiMUS


Cells are equipped with oxygen-sensing systems to mount a metabolic reprogramming when oxygen becomes limited involving the hypoxia-inducible factors (HIF1, HIF2 and HIF3). The role of this metabolic response in the context of tumour growth, metabolic disease as well as lung response to oxygen fluctuations will be briefly described. 


Julián Aragonés has participated in publications related to the role of HIF1 and HIF2 in tumour growth through the control of amino acid metabolism (Elorza et al. Molecular Cell 2012; Melendez-Rodriguez et al. Cell Reports 2019) as well as the role of HIF1α in obesity (Soro et al. Cell Reports 2016). He has received five invitations as an invited speaker at Keystone Symposia focusing on hypoxia biology (2008, 2012, 2015, 2015, 2018, 2023).

Host: Miguel López.

Attendance certificates will be provided upon request to cimus.xestion [at] (cimus[dot]xestion[at]usc[dot]es). Please bear in mind to register by writing clearly the name and surname on the printed sheet. We will not be responsible for amending the records of anyone who fails to do so.