Properly designed nanomaterials allow for combination treatment strategies with ionizing radiation for selective cytotoxicity (dose enhancement, radiation-induced drug release). Radiation alone can modulate the tumor microenvironment and tumor cell sensitivity by reoxygenation or killing of hypoxic cells in the peak dose. Spatial fractionation of radiation also primes the tumor microenvironment for immune infiltration.
Robert J. Griffin, PhD, professor of Radiation Oncology, studies the response of living tissue to radiotherapy and targeted drug delivery exploiting features of normal and tumor microvasculature. A major interest is to inhibit HIF1alpha and the hypoxic stress response of tumors to increase radiotherapy response and also the study of spatially fractionated radiation for therapeutic gain.
Host PI: Yolanda Prezado. NEW APPROACHES IN RADIOTHERAPY (NARA) Group. CiMUS
Attendance certificates will be provided upon request to cimus.xestion [at] usc.es (cimus[dot]xestion[at]usc[dot]es). Please bear in mind to register by writing clearly the name and surname on the printed sheet. We will not be responsible for amending the records of anyone who fails to do so.