"Redox regulation in Alzheimer's disease "
Mariana Inés Holubiec Lojo
IBioBA-MPSP - Instituto de Investigación en Biomedicina (Universidad de Buenos Aires)- Partner institute of the MaxPlanck Society
Theatre room, CiMUS
Abstract :
From several factors that are involved in Alzheimer?s disease (AD) initiation and progression, redox regulation has been highlighted as a relevant process that mediates changes affecting neuronal function. The development of human brain organoids from iPSCs allows us to analyse the effects of AD related mutations on redox regulation and mitochondrial homeostasis.
Bio:
Dr Holubiec did her PhD in Biochemistry at the University of Buenos Aires (Argentina). Post-doc position at IBioBA-MPSP (Argentina). Assistant professor at the Faculty of Medical Sciences (University of Buenos Aires). Worked at the University of Greifswald (Germany) and the University of Buenos Aires studying redox-related proteins in the central nervous system. Currently interested in thiol switches and redox regulation in neurodegenerative diseases. She is a researcher in transition to becoming a young PI at her home institution.
Hosted by Jesús R. Requena (Molecular Pathology of Rare Diseases Group)
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