Skip to main content
CiMUS Seminar

Trapping Ubiquitin (-like) E3 enzymes specific substrates. A hunting expedition

Román González-Prieto 

Group leader of Ubiquitin (-like) signaling and Proteomics group in Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Sevilla

3 November 2023 13:00–14:00

Theatre room, CiMUS


Protein modification by ubiquitin is one of the most important post-translational modifications, controlling virtually every process in eukaryotic cells. The human genome codes for more than 600 ubiquitin E3 enzymes, which confer substrate specificity. Determining E3-to-substrate wiring is a challenge, which we aim to address in the context of genome biology and human disease.



Román González-Prieto has recently started in CABIMER the ubiquitin signaling and proteomics group to study the role of ubiquitin(-like) modification in genome biology and human disease. Roman has made several contributions to the Ubiquitin(-like) field, including the E3-specific SUMO proteome (Salas-Lloret et al. 2023 Sci Adv) or the role of the tumor suppressor BRCA1/BARD1 E3 in DNA replication. Salas-Lloret et al. 2023 under review).  

Host: Clara Álvarez.

Attendance certificates will be provided upon request to cimus.xestion [at] (cimus[dot]xestion[at]usc[dot]es). Please bear in mind to register by writing clearly the name and surname on the printed sheet. We will not be responsible for amending the records of anyone who fails to do so.