The involvement of astrocyte calcium-dependent signaling in fear memory
João Filipe Oliveira
Group Leader, Brain Circuits and Neuron-Glia Adaptations. ICVS – School of Medicine, University of Minho, Braga (Portugal)
Theatre Room, CiMUS
About:
Astrocytes are highly active cells, displaying dynamic calcium elevations underlying the regulation of brain circuit function. However, the calcium-dependent signaling involved in these processes are poorly understood, representing a critical knowledge gap in this field. I will present results showing that astrocytes modulate hippocampal circuit structure and function through Foxo1 signaling to enhance fear memory.
Bio:
João Filipe Oliveira (JFO) graduated in Pharmaceutical Sciences in 2004 at the Faculty of Pharmacy - University of Porto. He obtained his PhD in neurophysiology in 2009 from the University of Leipzig, Germany. JFO received a Marie Curie Fellowship to join the ICVS (The Life and Health Sciences Research Institute), University of Minho, where he is currently a Principal Investigator on astrocyte modulation of cortico-limbic circuits and behavior. JFO is the chair of the Portuguese Glial Network.
Host PI: Olga Barca Mayo. Circadian and Glial Biology Group, CiMUS.
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