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Precision Medicine

Mobile Genomes

José Manuel Castro Tubío
Group Leader | Associate Professor
jose.mc.tubio@usc.es
 
Labs: P2L9, P0D9 (In silico lab)
Field of knowledge

The overall aim of our research is to identify and characterize new patterns and mechanisms of genomic structural alteration in disease, and the genetic causes of cancer transmissibility between individuals.

Research Lines

  • Patterns and mechanisms of structural variation in cancer development and disease.
  • Roles of retrotransposons and viruses in cancer and disease.
  • New genetic determinants of cancer under the sea.
  • Genetic causes of transmissible cancers.

Members

Daniel García Souto
Xunta de Galicia Postdoctoral Fellowship
daniel.garcia.souto@usc.es

 

Ana Pequeño Valtierra
Research Specialist Technician
Jorge Rodríguez Castro
Research collaborator
Ana Oitabén Fernández
Xunta de Galicia fellowship
Paula Otero Sánchez
FPU fellowship
Sonia Zumalabe Duro
PhD student
Iago Otero Coto
FPU fellowship
Martín Santamaría García
PhD student
Francisco Javier Temes Rodríguez
PhD student
Nuria Pereira Espasandín
FPI fellowship
Alejandro Viña Feás
PhD student
Ana Igea Fernández
Management Technician

Selected publications

MSIMEP: Predicting microsatellite instability from microarray DNA methylation tumor profiles

Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe

Daniel Garcia-Souto, Alicia L Bruzos, Seila Diaz, Sara Rocha, Ana Pequeño-Valtierra, Camila F Roman-Lewis, Juana Alonso, Rosana Rodriguez, Damian Costas, Jorge Rodriguez-Castro, Antonio Villanueva, Luis Silva, Jose Maria Valencia, Giovanni Annona, Andrea Tarallo, Fernando Ricardo, Ana Brato? Cetini?, David Posada, Juan Jose Pasantes, Jose MC Tubio

Assessing the elemental fingerprints of cockle shells (Cerastoderma edule) to confirm their geographic origin from regional to international spatial scales

Fernando Ricardo, Renato Mamede, Alicia L.Bruzos, Seila Díaz, JulienThébault, Eduardo Ferreira da Silva, Carla Patinha, RicardoCalado

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

Eva G. Álvarez, Jonas Demeulemeester, Paula Otero, Clemency Jolly, Daniel García-Souto, Ana Pequeño-Valtierra, Jorge Zamora, Marta Tojo, Javier Temes, Adrian Baez-Ortega, Bernardo Rodriguez-Martin, Ana Oitaben, Alicia L. Bruzos, Mónica Martínez-Fernández, Kerstin Haase, Sonia Zumalave, Rosanna Abal, Jorge Rodríguez-Castro, Aitor Rodriguez-Casanova, Angel Diaz-Lagares, Yilong Li, Keiran M. Raine, Adam P. Butler, Iago Otero, Atsushi Ono, Hiroshi Aikata, Kazuaki Chayama, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuhiro Maejima, Miguel G. Blanco, Xavier Forns, Carmen Rivas, Juan Ruiz-Bañobre, Sofía Pérez-del-Pulgar, Raúl Torres-Ruiz, Sandra Rodriguez-Perales, Urtzi Garaigorta, Peter J. Campbell, Hidewaki Nakagawa, Peter Van Loo & Jose M. C. Tubio

Pan-cancer analysis of whole genomes

ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium

Selected Results