Harnessing the power of natural products: towards understanding andrographolide as lead compound in the development of anti-inflammatory agents
Professor Christina Chai
Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore, Singapore.
Theatre room, CiMUS
About
This talk will focus on andrographolide, the principal bioactive compound of Andrographis paniculata, a well-known herb used in traditional Chinese and Ayurvedic medicine. I will share our research efforts aimed at unravelling the anti-inflammatory mechanisms of andrographolide and its related compounds. Through this work, the immense potential of harnessing natural products in the design and development of small-molecule therapeutics is highlighted.
Bio:
Professor Christina Chai earned her PhD in Organic Chemistry from the Australian National University and has held several prominent academic and research positions across the UK, Australia, New Zealand, and Singapore. Her research is focused on medicinal chemistry, particularly in the development of small-molecule therapeutics for diseases such as inflammation, infectious, and neurodegenerative diseases.
Host PI: Dolores Viña. Pharmacology of Chronic Diseases Group, CiMUS
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